Dosing and Infusion

Convenient dosing

Octagam® provides flexibility and choice with individualized and convenient dosing.

Octagam® is available in a wide range of vial sizes for customised dosing.3,4

Efficient handling

  • Available in two concentrations

  • No need for reconstitution

  • No need for an in-line filter

  • Choice of vial sizes to meet individual needs

  • Colour-coded packaging and vials

  • Integrated vial hanger for ease of use

  • Tamper-evident packaging

  • Storage at room temperature

For steady infusions octagam®5%

For fast infusions octagam®10%

IgG concentration³˒⁴

50 mg/mL

100 mg/mL

Shelf life³˒⁴

24 months

36 months

Maximum infusion speed³˒⁴

5 mL/kg/hour

7.2 mL/kg/hour

Storage³˒⁴ 2°C–8°C:

36 months

Storage³˒⁴ < 25°C:

24 months

9 months

Vial sizes³˒⁴, mL

50 mL, 100 mL, 200 mL, 500 mL

20 mL, 50 mL, 100 mL, 200 mL, 300 mL

Vial sizes³˒⁴, gram

2.5 g, 5 g, 10 g, 25 g

2 g, 5 g, 10 g, 20 g, 30 g

Octagam® is available in two concentrations: 5% and 10%

Dosing recommendation


Primary Immunodeficiency

0.2–0.8 g/kg every 3–4 weeks

Secondary Immunodeficiency (incl. congenital AIDS and HSCT)

0.2–0.4 g/kg every 3–4 weeks

Primary immune thrombocytopenia

0.8–1.0 g/kg on day 1 repeated within 3 days or 0.4 g/kg per day for 2–5 days

Guillain Barré syndrome

0.4 g/kg per day for 5 days

Kawasaki disease

1.6–2.0 g/kg divided over 2–5 days taken with ASA or 2.0 g/kg single dose taken with ASA

Chronic inflammatory demyelinating polyneuropathy

2.0 g/kg divided over ≤5 consecutive days every 4 weeks.*

(Octagam®10% only) Dermatomyositis

2.0 g/kg given divided in equal doses over 2-5 consecutive days every 4 weeks

*Initial dose recommendation. The maintenance dose must be adapted to the individual clinical response.

Infusion rate recommendations3,4

Initial infusion rate

Maximum infusion rate


0.02 mL/kg/min

0.08 mL/kg/min


0.01 mL/kg/min

0.12 mL/kg/min

*For Adult DM only:

  • Initial infusion rate : 0.01 mL/kg/min for first 30 minutes

  • Maximum (if tolerated): 0.04 mL/kg/min

For further recommendations for infusing DM patients, refer to specific information on dermatomyositis.

Please refer to the approved SPC or your local Product information for further information on octagam dosing and administration for all approved indications.

Octagam® IVIg tolerability considerations:

Octagam® is generally well tolerated.3,4

  • Common (>1%–<10%): hypersensitivity, headache, nausea, fever, fatigue, injection site reaction.

  • Uncommon (>0.1%–<1%): eczema, back pain, chest pain, chills.

The above list of adverse drug reactions (ADRs) are those identified in clinical trials with octagam®. For further information on ADRs and those that have been identified during post approval use of octagam®5% and octagam®10%, refer to the approved prescribing information.

Administration of octagam®

Certain severe adverse drug reactions reported with the administration of IVIg products may be related to the rate of infusion. The recommended infusion rates should be closely followed and patients closely monitored and observed for any symptoms throughout the infusion period, and in line with your local product administration policies.


3. octagam®5%. Summary of Product Characteristics. May 2021.

4. octagam®10%. Summary of Product Characteristics. May 2021.

This is an international website for octagam® and is intended for healthcare professionals outside the US. The information on this site is not country-specific and may contain information that is outside the approved indications in the country in which you are located.

IMPORTANT: The information on this website is based on the European Summary of Product Characteristics (EU SmPC).

If you wish to contact Octapharma please use the contact form on our corporate website.